Virginia Commonwealth University

VCU Massey Cancer Center

Causes and risk factors

What are the risk factors for Hodgkin’s disease?

Suggested risk factors for Hodgkin’s disease include the following:

  • Infection with infectious mononucleosis.
  • Age – Hodgkin’s disease occurs most often in people between ages 15 and 34, and in people over the age of 55.
  • Gender – Hodgkin’s disease is more common in men than in women.
  • Family history – brothers and sisters of those with Hodgkin’s disease have a higher-than-average chance of developing this disease.
  • Viruses – Epstein-Barr virus may be associated with an increased risk of Hodgkin’s disease.
  • Acquired immune deficiency syndrome (AIDS).
  • Organ transplantation.