Virginia Commonwealth University

VCU Massey Cancer Center

Massey opens clinical trial testing a combination of Viagra and chemo to treat advanced solid tumors

VCU Massey Cancer Center has developed and opened a Phase 1 clinical trial to study the effects of Viagra in combination with chemotherapy to treat patients with progressive, advanced solid tumors. The trial is a result of previous research conducted at Massey by a group of researchers including physician-scientist Andrew Poklepovic, M.D., who is the leading the trial as its principal investigator. Their research demonstrated that regorafenib (trade name Stivarga), a type of chemotherapy, interacts with Viagra (generic name sildenafil), a medication originally developed for erectile dysfunction, to kill tumor cells significantly better than regorafenib alone.

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Massey researchers find link between cancer gene and obesity

Virginia Commonwealth University Massey Cancer Center researchers have discovered that a gene known to cause cancer also may play a role in determining if someone becomes obese.

Recent discoveries suggest that the gene Astrocyte elevated gene-1 (AEG-1) could even be controlled with certain therapies to prevent or reverse obesity and obesity-related cancers.

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Massey researcher awarded grant to further develop a novel therapy for neuroblastoma

VCU Massey Cancer Center researcher Anthony Faber, Ph.D., was awarded a $46,000 grant from the Rally Foundation for Childhood Cancer Research and The Truth 365 to support his research to develop a new therapy for neuroblastoma, a rare type of cancer that develops in infants and young children.

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Massey welcomes William McGuire as director of the Phase I Solid Tumor Program

VCU Massey Cancer Center welcomes physician-researcher William McGuire III, M.D., as the director of the Phase 1 Solid Tumor Program. Also a medical oncologist and member of the Developmental Therapeutics research program at Massey, McGuire joined the VCU Department of Internal Medicine in fall 2014 as a professor of medicine in the Division of Hematology, Oncology and Palliative Care. An expert in gynecologic cancers and developmental therapeutics, McGuire was instrumental in the development of paclitaxel as part of the standard of care for advanced ovarian cancer.

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Massey researcher part of global scientific task force that found linkages between mixtures of commonly encountered chemicals and the development of cancer

A global scientific task force involving VCU Massey Cancer Center researcher Masoud Manjili, Ph.D., found that combinations of chemicals encountered every day in our air, food and water can lead to the development of cancer. Assembled by an NGO called “Getting to Know Cancer,” the task force consisted of 174 total scientists from prominent institutions in 28 countries who collaborated to tackle longstanding concerns over the linkages between mixtures of commonly encountered chemicals and the development of cancer.

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