How an aquarium pet became a scientific star in childhood cancer research
Seth Corey, M.D., M.P.H., joined VCU Massey Cancer Center and Children’s Hospital of Richmond at VCU (CHoR) in October 2015 as the chief of the Division of Hematology, Oncology, and Stem Cell Transplantation in the Department of Pediatrics. He is also the inaugural Children’s Hospital Foundation Endowed Chair in Pediatric Cancer Research, which is funded by a large grant from Children’s Hospital Foundation and a gift from Connor’s Heroes. Additionally, he is the co-leader of Massey’s Cancer Molecular Genetics research program and a professor of pediatrics and microbiology/immunology at the VCU School of Medicine. A board-certified pediatric oncologist and cancer researcher, Corey specializes in leukemias, bone marrow failure, and stem cell transplantation.
Massey researcher awarded $3 million to study the effect of blood cell stimulation on the development of adolescent leukemia and bone marrow disorders
Massey program leader, researcher and physician Seth Corey M.D., M.P.H., was awarded more than $3 million in grant funding from the National Heart, Lung and Blood Institute (NHLBI) for a four-and-a-half-year study on the evolution of a blood cell deficiency to pre-leukemia. The research aims to determine whether a common treatment for the condition acts as a contributor to the development of leukemia or other life-threatening bone marrow disorders.
VCU Massey researchers uncover process that drives prostate cancer metastasis
Researchers at VCU Massey Cancer Center have uncovered a novel function of the gene PLK1 (polo-like kinase 1) that helps prostate cancer cells metastasize (spread) to other parts of the body. This mechanism highlights new potential targets for cancer therapies and challenges the previous understanding of PLK1’s role in cancer growth and progression.
VCU scientists develop computer models simulating stem cell transplant recovery
Scientists at Virginia Commonwealth University have developed computer models that can simulate the recovery of the immune system in patients undergoing stem cell transplants. In two recent studies, they reinforce the potential of using DNA sequencing and computer modeling to predict which stem cell transplant recipients might suffer complications such as graft-versus-host-disease, a condition where the donor’s immune system attacks the recipient’s body. The studies build upon prior research by scientists at VCU Massey Cancer Center, the VCU Center for the Study of Biological Complexity and VCU’s Department of Psychiatry and Statistical Genomics that found evidence that the immune system may be modeled as a dynamical system.
First-of-its-kind head and neck cancer immunotherapy clinical trial opens at Massey
VCU Massey Cancer Center is recruiting participants for an international phase 2 clinical trial testing the first immune checkpoint inhibitors for head and neck cancer. Immune checkpoint inhibitors are drugs that cause the immune system to recognize and attack cancer cells, and they have shown dramatic results in treating certain types of skin and lung cancers.