VCU Massey Cancer Center



Collaborative research

The collaborative research function involves a long-term investment of time and effort by the Biostatistics Shared Resource (BSR) Core faculty involved with the Massey investigator. Examples include front-end involvement on grant proposals as well as work on funded grants. BSR Core faculty assist Massey researchers in developing and designing projects, writing biostatistical sections of the grant proposal, developing data collection instruments, performing biostatistical analyses at interim points and, at the end of a trial, developing new methodologies if needed, and assisting with writing the results from the trials for publication.

Methodologic research

Methodologic research in biostatistics originates from the shared resource’s collaborations and consultations with Massey researchers. Examples of such research include design of Phase II trials with retrospective biomarkers, bivariate twin methodology for multiple cancers and microarray data analysis methods.


BSR Core faculty provide limited short-term advice on biostatistical issues involved in the design, conduct and analysis of research projects. Examples include preparing a study plan from the requirements of the statistical design, developing appropriate randomization and stratification procedures, managing data and assisting with the conduct of pre-clinical and clinical studies through provision of interim analyses.


Training is conducted through both seminars and individual sessions with investigators. BSR Core faculty members also train postdoctoral scientists and clinical fellows through the clinical research and biostatistics training track.

Participation in monitoring system

The BSR Core faculty actively participates in Massey’s Protocol Review and Monitoring System (PRMS). All investigator-initiated protocols must now involve a biostatistician and must be reviewed by an independent biostatistician.