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Robert M. Tombes, Ph.D.

Research program member: Cancer Cell Signaling

Box 842012
57 E. 25th St.
Richmond, VA 23298

804-827-0141

Email: rtombes@vcu.edu

Affiliations

Professor, Biology, College of Humanities and Sciences
Professor, Biochemistry and Molecular Biology, School of Medicine

Education

PhD, University of Washington (1986)

Research description

My current research is conducted in collaboration with Dr. Sarah C. Rothschild, a pediatric geneticist who studies leukemia using zebrafish models. My laboratory has used zebrafish and human cancer cells in culture to study signal transduction pathways that depend on activation by calcium ions. My research has focused on the role of calcium-dependent protein kinases to activate cell proliferation and differentiation pathways in zebrafish and human cells in culture. This work has been relevant to inherited disorders, such as polycystic kidney disease, cardiac defects, and leukemia.

Research keywords

Animal models,Bioinformatics,Cancer cell biology,Cell cycle regulation,Cell signaling,Epigenetics,Oncogenes,Proteomics,Signal transduction

Published research

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