Amir Toor, M.D.
Massey Cancer Center research program membership
Developmental Therapeutics
Department affiliations
Professor,
Division of Hematology-Oncology and Palliative Care,
Department of Internal Medicine,
School of Medicine
Education
MD, King Edward Medical University, Pakistan (1900)
Research description
My work focuses on understanding the molecular basis of cellular immunotherapy of hematological malignancies. I have conducted several clinical trials in the last decade, including epigenetic induction of adaptive immune response, using azacitidine in patients with multiple myeloma, and developing reduced intensity conditioning regimens for patients with lymphoma. More recently, and in collaboration with my colleagues at VCU and Massey, we've looked at the use of ascorbic acid to reduce the impact of regimen related toxicities in allograft recipients. We have also used DNA sequencing to understand the molecular basis of allo-immune responses in stem cell transplantation, which lead to mathematical algorithms that elucidate the rules governing these interactions.
Disease focus of research
Hematologic Malignancies
Research keywords
Clinical trials,Epigenetics,Genomics,Immunotherapy,Inflammation,Molecular medicine,Precision medicine
Published research (during tenure as a Massey Cancer Center member)
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