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Iain M. Morgan, Ph.D.

Research program member: Cancer Molecular Genetics

Box 980566
1101 E. Leigh St.
Richmond, VA 23289

804-828-0149

Email: immorgan@vcu.edu

Affiliations

Professor, Philips Institute for Oral Health Research, School of Dentistry

Education

PhD, University of Glasgow, Scotland (1989)

Research description

We are interested in the molecular mechanisms that result in human papillomavirus infections progressing to cancers. We study viral replication and how viral replication proteins interact with that of the host with the ultimate goal of blocking replication and promoting death of the HPV cancer cells. We are also investigating how the virus promotes segregation of its genome in infected cell during mitosis, and how the virus regulates transcription from the host genome. We use a combination of primary keratinocytes, cancer cell lines and patient derived xenografts (PDX) in our studies.

Research keywords

Animal models,Bioinformatics,Cancer cell biology,DNA damage,Mitosis,Oncogenes,Other

Published research

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