Brian Wattenberg, Ph.D.
Massey Cancer Center research program membership
Cancer Cell Signaling
Department affiliations
Professor,
Department of Biochemistry and Molecular Biology,
School of Medicine
Education
PhD, Washington University (1981)
Research description
We are studying how levels of sphingolipids are regulated. Sphingolipids are a class of lipids that have diverse functions in biology, including structural roles in membranes and as signaling molecules. Some members of this family of lipids promote proliferation and some promote cell death, both processes crucial to cancer biology. We hope that through a detailed understanding of how these levels are regulated, we will be able to design therapeutic approaches that alter metabolism to promote the death of cancer cells.
Disease focus of research
Brain & nervous system
Research keywords
Apoptosis,Cancer cell biology,Lipid signaling,Proteomics
Published research (during tenure as a Massey Cancer Center member)
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