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Brian Wattenberg, Ph.D.

Research program member: Cancer Cell Signaling

Box 980614
1101 E. Marshall St.
Richmond, VA 23298

804-827-1257

Email: brian.wattenberg@vcuhealth.org

Affiliations

Professor, Biochemistry and Molecular Biology, School of Medicine

Education

PhD, Washington University (1981)

Research description

We are studying how levels of sphingolipids are regulated. Sphingolipids are a class of lipids that have diverse functions in biology, including structural roles in membranes and as signaling molecules. Some members of this family of lipids promote proliferation and some promote cell death, both processes crucial to cancer biology. We hope that through a detailed understanding of how these levels are regulated, we will be able to design therapeutic approaches that alter metabolism to promote the death of cancer cells.

Research keywords

Apoptosis,Cancer cell biology,Lipid signaling,Proteomics

Published research

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