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Wook-Jin Chae, Ph.D.

Massey Cancer Center research program membership

Cancer Cell Signaling

Department affiliations

Assistant Professor, Department of Microbiology and Immunology, School of Medicine

Education

PhD, Yonsei University, South Korea (2006)
MS, Yonsei University, South Korea (2001)

Research description

My current cancer-related research is focused on how the Wnt antagonist DKK1 modulates chronic inflammation in the tumor microenvironment. We are particularly interested in natural killer (NK) cells with their ability to kill stressed tumor cells. We use a variety of tools to address this question, such as multi-color flow cytometry and immunoassays using fluorescent probes. We also use all the basic molecular/cellular biological techniques to address our question. Along with our basic research, we pursue a novel translational approach for cancer immunotherapy in combination with chemo/radiotherapy and other immune checkpoint inhibitors (ICI).

Disease focus of research

Breast, Hematologic Malignancies, Prostate, Brain & nervous system, Gynecologic, Hepatic, Respiratory/lung

Research keywords

Animal models,Biomarkers,Cell signaling,Immunotherapy,Inflammation,Metabolism,Metastasis,Translational science,Tumor microenvironment

Published research (during tenure as a Massey Cancer Center member)

Search In PubMed

Contact information

Email: wook-jin.chae@vcuhealth.org