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Rebecca Martin, Ph.D.

Massey Cancer Center research program membership

Non-aligned member

Massey Cancer Center leadership roles

Director, Flow Cytometry Shared Resource

Department affiliations

Assistant Professor, Department of Microbiology and Immunology, School of Medicine

Education

PhD, Virginia Commonwealth University (2014)

Research description

My laboratory is an immunology lab that has extensive experience studying high parameter flow cytometric characterization of different disease states. Recently we have focused our work on the regulation of the immune system in obesity induced inflammation. Our current model has identified a mechanistic pathway connecting the health of the fat pad and the liver, linking an unhealthy adjacent fatpad to a pre-cancerous state. Another collaborative project involves the examination of the DNMTi, guadecitabine in a triple negative breast cancer model. We utilize this drug in low dose to reduce side effects and combine it with other FDA approved treatments to reduce immunosuppressive cell types in breast cancer and harness the potential immune boosting power of DNMTis.

Disease focus of research

Breast, Hepatic

Research keywords

Animal models,Cancer cell biology,Immunotherapy,Inflammation,Metabolism,Obesity

Published research (during tenure as a Massey Cancer Center member)

Search In PubMed

Contact information

Email: rebecca.martin@vcuhealth.org