Rebecca Martin, Ph.D.
Massey Cancer Center research program membership
Massey Cancer Center leadership roles
Director, Flow Cytometry Shared Resource
Department of Microbiology and Immunology,
School of Medicine
PhD, Virginia Commonwealth University (2014)
My laboratory is an immunology lab that has extensive experience studying high parameter flow cytometric characterization of different disease states. Recently we have focused our work on the regulation of the immune system in obesity induced inflammation. Our current model has identified a mechanistic pathway connecting the health of the fat pad and the liver, linking an unhealthy adjacent fatpad to a pre-cancerous state. Another collaborative project involves the examination of the DNMTi, guadecitabine in a triple negative breast cancer model. We utilize this drug in low dose to reduce side effects and combine it with other FDA approved treatments to reduce immunosuppressive cell types in breast cancer and harness the potential immune boosting power of DNMTis.
Disease focus of research
Animal models,Cancer cell biology,Immunotherapy,Inflammation,Metabolism,Obesity
Published research (during tenure as a Massey Cancer Center member)
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