Jason Newton, Ph.D.
Research program member: Cancer Cell Signaling
1101 E Marshall St.
Richmond, VA 23298
Instructor, Biochemistry and Molecular Biology, School of Medicine
PhD, Virginia Commonwealth University (2013)
My current research focus includes examining the roles that sphingosine kinase 1 and sphingosine kinase 2 play in the development of cancer. I examine the role that de novo sphingolipid biogenesis plays in helping cancer cells avoid cellular death after chemotherapeutic treatment. This work focuses on sphingolipid metabolism, namely the balance between the pro-life metabolite sphingosine 1 phosphate and pro-death metabolite ceramide.
Autophagy,Cancer cell biology,Cell signaling,Drug discovery,Lipid signaling,Metabolism