Tomasz Kordula, M.S., Ph.D.
Research program member: Cancer Cell Signaling
1101 E. Marshall St.
Richmond, VA 23298-0614
Professor, Biochemistry and Molecular Biology, School of Medicine
PhD, Jagiellonian University, Poland (1992)
MS, Jagiellonian University, Poland (1988)
We are studying the role of transcription factors, which are normally associated with astrocyte-specific and inflammatory gene expression, in development and progression of glioblastoma multiforme. We are using spontaneous mouse glioma model that utilizes oncogenic lentiviruses. Currently, we are examining the roles of YY1, RelB, and IRF1 play in glioma development and progression.
Animal models,Bioinformatics,Cancer cell biology,Cell signaling,Inflammation,Signal transduction